Category: MTHFR

DAO Deficiency and Histamine: The Unlikely Connection

DAO Deficiency and Histamine: The Unlikely Connection

What does it mean? We live in a time when we can choose what to eat. But in our endeavour to be healthy, what are we doing to histamine levels? How is this affecting us? For most of us, histamine is just another chemical compound that we associate with allergies.  It’s good for the most

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Role of Vitamin B12 in Pregnancy Related Obesity

Role of Vitamin B12 in Pregnancy Related Obesity

You are B12 deficient when your serum B12 is <150 pmol/l according to our Australian Labs. But the reality is that this number is way too low and people who have a B12 level this low will surely show signs of neurological dysfunction. There is sufficient research to suggest that this level should be 500pmol/L

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Step 2 in MTHFR Support: How To Choose The Right B12 For You

Step 2 in MTHFR Support: How To Choose The Right B12 For You

We’ve written plenty about the importance of B12 intake with regards to the MTHFR gene. The best sources of B12 will always be the food you eat (specially meat) but what if you need to get more B12? You can only eat so much food in one day and sometimes B12-rich foods aren’t abundant. This is

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10 Health Tips For Those With Deficiencies

Step 1 in MTHFR Support: 10 Health Tips For Those With Deficiencies

Make sure you’ve read our article on MTHFR so you’ll have a little background on this mutation.  What is Methylation? Methylation is the process where a carbon and three hydrogen atoms (aka a methyl group) attach itself to an enzyme in your body. When the methyl group is attached to an enzyme, the said enzyme performs a

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Histamine and Methylation

Histamine and Methylation

Histamine Histamine is a hydrophilic vasoactive amine derived from histidine through carboxylation by L-histidine decarboxylase1. Histamine, once formed, can be stored or rapidly undergo deamination or demethylation, which is catalyzed by diamine oxidase (DAO) or histamine-N-methyltransferase (HNMT) respectively. IgE antibodies on immune cells cause them to degranulate, releasing specific alkaloids and amines capable of displacing

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Genes And B12 Deficiency

Genes And B12 Deficiency

Vitamin B12 is essential to human health. However, some people have inherited conditions that leave them unable to process vitamin B12. As a result they are prone to serious health problems, including developmental delay, psychosis, stroke and dementia. Genes and B12 Deficiency An international research team recently discovered a new genetic disease related to vitamin

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Functional Benefits of Hydroxocobalamin Supplements

Functional Benefits of Hydroxocobalamin Supplements

Hydroxocobalamin is a precursor to methylcobalamin and Vitamin B12. It is usually prescribed in conditions where B12 cannot be properly absorbed in the gut. It is manufactured naturally as a therapeutic agent with the help of your gut bacteria.1 Hydroxocobalamin is red in color and plays an integral part in DNA replication and synthesis, proper

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Methylcobalamin

Methylcobalamin

Methylcobalamin, also referred to as MeB12 and MeCbl, is a member of the cobalamin family and is one of the naturally occurring coenzyme forms of cobalamin found in the human body. Structurally, Methylcobalamin exists in octahedral form with Cobalt (III) at the center containing metal alkyl bonds[1]. It is considered an equivalent to cobalamin and

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Are You Suffering From B12 Deficiency?

Are You Suffering From B12 Deficiency?

Are You Suffering From B12 Deficiency? I believe one of the most overlooked deficiencies in Australia, and probably worldwide, is B12 deficiency. [thrive_link color=’purple’ link=’https://forms.gle/wdS2uNAxDaisBDw67′ target=’_blank’ size=’medium’ align=”]TAKE THE B12 QUIZ[/thrive_link] Our reference ranges are too low and so people don’t really notice when they’re B12 deficient. Just this morning I saw a beautiful couple for fertility

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Carolyn Ledowsky

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