What is MTHFR?

Watch our Introductory Webinar Recording on What is MTHFR Below:

MTHFR stands for Methylene-TetraHydroFolate Reductase
It is an enzyme that converts folate you eat into the active form (5-Methyltetrahydrofolate).

You can see from the pathway below that the folate you eat (DHF – dihydrofolate) has to be converted via many steps to the active folate 5-MTHFR.

The MTHFR enzyme affects this at the last step. So if you have a mutation in the gene then its going to be affecting how much active folate you have available.

Folate Metabolism

What is Folate

The MTHFR Gene

Current MTHFR Testing

The Methylation Cycle

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