Histamine Histamine is a hydrophilic vasoactive amine derived from histidine through carboxylation by L-histidine decarboxylase1. Histamine, once formed, can be stored or rapidly undergo deamination or demethylation, which is catalyzed by diamine oxidase (DAO) or histamine-N-methyltransferase (HNMT) respectively. IgE antibodies on immune cells cause them to degranulate, releasing specific alkaloids and amines capable of displacing
Vitamin B12 is essential to human health. However, some people have inherited conditions that leave them unable to process vitamin B12. As a result they are prone to serious health problems, including developmental delay, psychosis, stroke and dementia. Genes and B12 Deficiency An international research team recently discovered a new genetic disease related to vitamin
Hydroxocobalamin is a precursor to methylcobalamin and Vitamin B12. It is usually prescribed in conditions where B12 cannot be properly absorbed in the gut. It is manufactured naturally as a therapeutic agent with the help of your gut bacteria.1 Hydroxocobalamin is red in color and plays an integral part in DNA replication and synthesis, proper
Methylcobalamin, also referred to as MeB12 and MeCbl, is a member of the cobalamin family and is one of the naturally occurring coenzyme forms of cobalamin found in the human body. Structurally, Methylcobalamin exists in octahedral form with Cobalt (III) at the center containing metal alkyl bonds[1]. It is considered an equivalent to cobalamin and
Are You Suffering From B12 Deficiency? I believe one of the most overlooked deficiencies in Australia, and probably worldwide, is B12 deficiency. [thrive_link color=’purple’ link=’https://forms.gle/wdS2uNAxDaisBDw67′ target=’_blank’ size=’medium’ align=”]TAKE THE B12 QUIZ[/thrive_link] Our reference ranges are too low and so people don’t really notice when they’re B12 deficient. Just this morning I saw a beautiful couple for fertility
We learned previously that there are differences between folic acid and methyl folate when they are taken by pregnant women. New scientific studies reveal more of the risks of folic acid intake in pregnancy. Additionally, even though adequate folate intake is necessary in the safety and health of pregnancy, new research shows that folic acid
There is no question that the future of medicine will be in analysing a person’s genetics, with a detailed family history and addressing the genetic inefficiencies of that person. As naturopaths, we will be required to understand more of the mechanisms that drive a person to ill health. Yes, the environment is key, however, there
Is your home filled with hormone, MTHFR and fertility friendly products? Endocrine Disruptors (ED) are a group of synthetic, man-made chemicals that have permeated many/most aspects of our modern lives. Known to have negative effects on the reproductive system, endocrine disruptors have the capacity to damage or kill cells, influence genetic expression and alter the
Bisphenol A: BPA or Bisphenol A is a common chemical found in plastics and has been in large scale industrial use since the 1960’s. This chemical is found primarily in two substances – polycarbonate plastics and epoxy resins, with consumers then exposed to BPA via using plastic storage containers, drinking from plastic water bottles, eating foods
Folate is important for the overall methylation and synthesis of DNA, which is critical to your baby’s development. But it’s particularly essential for the growth and replication of neural cells. We see this in cases of neural tube defects, and pregnant women know to increase folate consumption to prevent them. However, folate deficiency during pregnancy
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