How Histamine Imbalance Could be Ruining Your Mood One of the many functions of histamine in the body is to act as a neurotransmitter, where it helps regulate important brain functions such as alertness, attention, learning, memory, stress response, sleep-wake cycles, and sexual function. When the body’s histamine levels go out of control, many behavioral
Histamine Intolerance Histamine intolerance (HIT) is a relatively common condition. The occurrence of HIT is increasing more these days, although the actual mechanism is not completely resolved. When it comes to HIT, we always think of some certain mutations in the DAO gene but HIT is not only because of this. We must also incorporate
The female hormone estrogen may play a role in the development of histamine intolerance. This seems plausible since women consist of the majority who suffer from this. One explanation is that estrogen and histamine reinforce each other which means estrogen triggers histamine release. In turn, histamine causes increased estrogen production. But that is just among
Histamine is a natural substance produced by the human body and is a substance with many important functions. Histamine was first isolated in 1907 by Windaus and Vogt, but research is ongoing in both health and disease since its initial description more than a hundred years ago.1 Histamine was considered an amine that was only
Cardiovascular disease is a major health concern. Multiple co-morbidities are responsible for increasing the cardiovascular risks some of which include hypercholesterolemia, diabetes, smoking and hypertension. [1] All these diseases are directly or indirectly related to the plaque development inside the arteries otherwise known as atherosclerosis. The vascular tone of blood vessels is regulated by the
What does it mean? We live in a time when we can choose what to eat. But in our endeavour to be healthy, what are we doing to histamine levels? How is this affecting us? For most of us, histamine is just another chemical compound that we associate with allergies. It’s good for the most
You are B12 deficient when your serum B12 is <150 pmol/l according to our Australian Labs. But the reality is that this number is way too low and people who have a B12 level this low will surely show signs of neurological dysfunction. There is sufficient research to suggest that this level should be 500pmol/L
Histamine and Gut Health: The unlikely connection between allergies and our own gut microbes. If you think the role of histamine is only in allergy and allergic reactions, you’re quite mistaken. Don’t worry, it’s totally normal not to know these things since many of us are not aware of histamine’s other equally important functions, some
We’ve written plenty about the importance of B12 intake with regards to the MTHFR gene. The best sources of B12 will always be the food you eat (specially meat) but what if you need to get more B12? You can only eat so much food in one day and sometimes B12-rich foods aren’t abundant. This is
Make sure you’ve read our article on MTHFR so you’ll have a little background on this mutation. What is Methylation? Methylation is the process where a carbon and three hydrogen atoms (aka a methyl group) attach itself to an enzyme in your body. When the methyl group is attached to an enzyme, the said enzyme performs a
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