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Methylation, MTHFR and Gastric Cancer

Song et al (2013) examined the association between several cancer related genes with the prevalence of MTHFR in patients with gastric cancer. Hypermethylation of these cancer related genes was highly evident, which could therefore be used as predictive biomarkers in the detection of gastric cancer. Patients with MTHFR 677TT mutations were found to have hypermethylation of genes within cancer tissue.

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