When a patient presents with low motivation, emotional flatness, addictive behaviours, or an inability to complete even simple tasks, it’s easy to mistake them as “non-compliant” or “uncommitted.” But what if the problem isn’t psychological? What if it’s biochemical? In clinical genomics, we now understand that fast COMT activity—driven by genetic variation—can deplete dopamine levels …
Serotonin has become a household name. It’s often blamed for depression, and targeted by SSRIs. But as any functional practitioner knows, it’s rarely that simple. In truth, serotonin is influenced by a matrix of genetic factors, cofactors, and environmental inputs—and if you don’t understand these, you’ll struggle to get lasting results with your patients. Today, …
The Science of Serotonin: How MAOA, BH4, and Inflammation Hijack Mood Read More »
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