MTHFR Support

Cleft Palate

Cleft Palate

Share This Post

What is Cleft Lip or Palate?

A fissure in the midline  of the palate due to the failure of the two sides to fuse in embryonic development. Only part of the palate may be affected, or the cleft may be extend the full length with bilateral clefts at the front of the mouth. The cleft may be accompanied by a split lip and tooth formation disturbances.

Cleft palates can be corrected by surgery.

Research

Mothers of children born with Cleft Lip or Palate were examined for involvement of the MTHFR C677T & A1298C mutation, folic acid supplementation and environmental exposure. Ibarra-Lopez et al (2013) found there to be an increased risk of having a child with C L/P in mothers with C667T or 677TT mutation in comparison to those with the normal C677C genotype. A lack of folate supplementation in the first trimester also contributed to the development of C L/P, which was further compounded by the presence of T677T or C677T MTHFR polymorphism. No association with A1298C in mothers and children with C L/P was found.

Article Here

 

 

Related Posts

Glowing Carrot Ginger Turmeric Soup
MTHFR

Glowing Carrot Ginger Turmeric Soup

Ingredients: 1 Tbsp coconut or olive oil ½ cup chopped shallot (2 shallots, or ½ an onion) 2 Tbsp chopped, peeled turmeric 2 Tbsp chopped, ...
Read More →
American Heart Association should re-think their status on MTHFR mutations
MTHFR

American Heart Association should re-think their status on MTHFR mutations

Recently Stephan Moll and Elizabeth Varga wrote on Homocysteine and MTHFR Mutations in this months American Heart Association journal, while much of the information about homocysteine ...
Read More →
Brown Rice Pilaf
MTHFR

Brown Rice Pilaf

Ingredients: 1 small sweet potato, chopped coarsely olive oil spray 1½ cups vegetable stock 1 tsp olive oil 1 small brown onion, finely chopped 1 ...
Read More →
Circadian Rhythm and Fertility
MTHFR

Circadian Rhythm and Fertility

To everything, there is a season. A time. A purpose. Nature and all earthly living beings follow cycles and rhythms. And, your body feels best ...
Read More →
How does MTHFR affect your fertility?
Genes

How does MTHFR affect your fertility?

As soon as you plan to get pregnant, it’s pretty normal that you want to know as much as you can about the whole process ...
Read More →
Do MTHFR polymorphisms make you more susceptible to COVID-19?
MTHFR

Do MTHFR polymorphisms make you more susceptible to COVID-19?

Our genes shape most of what we look like and how our bodies work – the very fabric of our being. Humanity’s understanding of genetics ...
Read More →
Scroll to Top
Carolyn Ledowsky

Stay Connected!

Sign up for our monthly newsletter with current MTHFR research, health tips, recipes, special offers and news about upcoming events including Carolyn’s live Q&A.

Subscribe