A paper published recently has shown that fathers preconception smoking is associated with a decrease in DNA methylation in the offspring. This was associated with asthma in the offspring. This is consistent with research that suggests that disturbances in the epigenome through parental exposures even before the child is conceived
A newly published 2024 study concludes that long-term supplemental dose of FA leads to prolongation of Oestrous cycle of Sprague Dawley rats. The study showed that continuous use of folic acid @1mg per day disrupted sex hormones including Luteinising hormone (LH) and Follicle stimulating hormone (FSH) which leads to higher
A brand New 2024 study shows that MTHFR C677T is linked to egg quality. This study out of Iraq looked at the MTHFR C677T polymorphism and its affect on IVF procedures ICSI (intracytoplasmic sperm injection). It included 85 infertile women undergoing ICSI treatment, where they tested oocytes (egg), total embryos,
In preconception and pregnancy, women are encouraged to take folic acid-based supplements over and above food intake. The upper tolerable limit of folic acid is 1000 mcg per day; however, this level was determined to avoid masking a vitamin B12 deficiency and not based on folic acid bioavailability and metabolism.
A recent study out of China published in October 2023 shows that the MTHFR C677T TT homozygous polymorphism is associated with 13% higher risks of stroke. This was a study of 156,253 participants and showed around 21% of the Chinese population studied were TT homozygous MTFHR C677T. Those who were
The following study shows that low folate levels were significantly lower in women diagnosed with CIN3. HPV or human papilloma virus is a precursor to high grade precancerous lesions. So too abnormal DNA methylation combined with low folate appears to be a key determinant of HPV infections that proceed to
Breast cancer (BCa) has many well-known risk factors, including age, genetics, lifestyle, and diet; however, the influence of the gut microbiome on BCa remains an emerging area of investigation. This study explores the connection between the gut microbiome, dietary habits, and BCa risk. LINK TO ARTICLE DOI: 10.3390/nu15214628
This review delves into the intricate relationship between excess folate (vitamin B9) intake, especially its synthetic form, namely, folic acid, and its implications on health and disease. Link to Article: https://www.mdpi.com/2072-6643/15/21/4699?utm_campaign=releaseissue_nutrientsutm_medium=emailutm_source=releaseissueutm_term=titlelink4
“This paper highlights that magnesium glycinate plays a role in helping to regulate the electrical impulses that control the heart’s rhythm, thereby helping to prevent arrhythmias and promoting a regular heartbeat” Link to article here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703169/ and this article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852744/
“Supplementation of magnesium appears to improve subjective and objective measures of insomnia in elderly people and may become a useful instrument in managing sleep disorders in the elderly, which could also be extended as a helpful aid to the general population.” Link to article here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703169/
A paper published recently has shown that fathers’ preconception smoking is associated with a decrease in DNA methylation in the offspring. This was associated with asthma in the offspring. This is consistent with research that suggests that disturbances in the epigenome through parental exposures even before the child is conceived
Background: In preconception and pregnancy, women are encouraged to take folic acid-based supplements over and above food intake. The upper tolerable limit of folic acid is 1000 mcg per day; however, this level was determined to avoid masking a vitamin B12 deficiency and not based on folic acid bioavailability and
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