African American (EA) women are more likely than European American (EA) women to be diagnosed with breast cancer at a young age and to develop tumours with a poor prognosis, with this racial difference largely unexplained. While nutrients involved in the methylation cycle have been linked with breast cancer, Gong

Wu et al (2014) investagted whether genetic mutations of the SHMT, MS, MTRR and CBS genes can affect Homocysteine (Hcy) levels and are associated with breast cancer. Results showed those with elevated Hcy levels had a 4.45 increased risk of breast cancer when comparing breast cancer patients with healthy controls.

Wu et al (2014) investigated whether genetic mutations of the SHMT, MS, MTRR and CBS genes can affect Homocysteine (Hcy) levels and are associated with breast cancer. Results showed those with elevated Hcy levels had a 4.45 increased risk of breast cancer when comparing breast cancer patients with healthy controls.

High homocysteine levels and mutations in the genes that regulate it have been found in bipolar, depressive and schizophrenic patients. Therefore, Permoda-Osip et al (2014) wished to understand the correlation between bipolar mood disorder and the mutations in genes that encode MTHFR, CBS, MTR and MTRR enzymes. 120 bipolar patients

High homocysteine levels and mutations in the genes that regulate it have been found in bipolar, depressive and schizophrenic patients. Therefore, Permoda-Osip et al (2014) wished to understand the correlation between bipolar mood disorder and mutations in genes that encode MTHFR, CBS, MTR and MTRR enzymes. Bipolar patients were screened

Weng et al (2014) conducted research on young mice to examine how extensively DNA methylation within the brain is regulated by nutrition early in life. The post natal brain exhibit stimulus-induced methylation changes due to their environment, lifestyle and diet. The thalamus and hippocampus of malnourished mice were compared to

Weng et al (2014) conducted research on young mice to examine how extensively DNA methylation within the brain is regulated by nutrition early in life. The thalamus and hippocampus of malnourished mice were compared to the brains of normal mice, with the two regions showing differences in their levels of

Rai et al (2014) desired to discover the differences in the prevalence of MTHFR C677T and A1298C prevalence in normal and colon cancer tissue. Therefore, DNA isolated from tumour tissue was examined and compared with normal tissue in 155 colon cancer patients, whilst also being compared to the genotype frequencies

Rai et al (2014) wished to discover the differences in MTHFR prevalence in normal and colon cancer tissue. Therefore, DNA isolated from tumour tissue was examined and compared with normal tissue of colon cancer patients.  Results found the frequencies of MTHFR C677T and A1298C were significantly different between tumour and

Finding an accurately marker in the follow up of women diagnosed with the human papillomavirus type 16 (HPV16) maybe improve rates of cervical cancer prevention.  The authors Brandsma et al (2014) previously studied 113 samples of HPV genes and discovered different levels of methylation at different levels of pre-malignancy (cancer

Finding an accurately marker in the follow up of women diagnosed with the human papillomavirus type 16 (HPV16) maybe improve rates of cervical cancer prevention.  The authors Brandsma et al (2014) previously studied 113 samples of HPV genes and discovered different levels of methylation at different levels of pre-malignancy (cancer

Song et al (2013) examined the association between cancer related genes (named P16, MGMT and HMLH1) with the prevalence of MTHFR in patients with gastric cancer. 322 patients with gastric cancer were examined. Hypermethylation of the P16, MGMT and HMLH1 genes found within cancer tissue were found to be 75.2%,