Stephen Hawking is a world renowned English theoretical physicist, cosmologist, and author. He is what many people call a genius visionary whose knowledge is only limited by what science has yet to find out. Despite his tremendous achievements, he is currently much more recognized to be the symbol of a crippling disease: Amyotrophic Lateral Sclerosis
Histamine Intolerance Histamine intolerance (HIT) is a relatively common condition. The occurrence of HIT is increasing more these days, although the actual mechanism is not completely resolved. When it comes to HIT, we always think of some certain mutations in the DAO gene but HIT is not only because of this. We must also incorporate
Cardiovascular disease is a major health concern. Multiple co-morbidities are responsible for increasing the cardiovascular risks some of which include hypercholesterolemia, diabetes, smoking and hypertension. [1] All these diseases are directly or indirectly related to the plaque development inside the arteries otherwise known as atherosclerosis. The vascular tone of blood vessels is regulated by the
What does it mean? We live in a time when we can choose what to eat. But in our endeavour to be healthy, what are we doing to histamine levels? How is this affecting us? For most of us, histamine is just another chemical compound that we associate with allergies. It’s good for the most
We’ve written plenty about the importance of B12 intake with regards to the MTHFR gene. The best sources of B12 will always be the food you eat (specially meat) but what if you need to get more B12? You can only eat so much food in one day and sometimes B12-rich foods aren’t abundant. This is
Make sure you’ve read our article on MTHFR so you’ll have a little background on this mutation. What is Methylation? Methylation is the process where a carbon and three hydrogen atoms (aka a methyl group) attach itself to an enzyme in your body. When the methyl group is attached to an enzyme, the said enzyme performs a
Histamine Histamine is a hydrophilic vasoactive amine derived from histidine through carboxylation by L-histidine decarboxylase1. Histamine, once formed, can be stored or rapidly undergo deamination or demethylation, which is catalyzed by diamine oxidase (DAO) or histamine-N-methyltransferase (HNMT) respectively. IgE antibodies on immune cells cause them to degranulate, releasing specific alkaloids and amines capable of displacing
Vitamin B12 is essential to human health. However, some people have inherited conditions that leave them unable to process vitamin B12. As a result they are prone to serious health problems, including developmental delay, psychosis, stroke and dementia. Genes and B12 Deficiency An international research team recently discovered a new genetic disease related to vitamin
Hydroxocobalamin is a precursor to methylcobalamin and Vitamin B12. It is usually prescribed in conditions where B12 cannot be properly absorbed in the gut. It is manufactured naturally as a therapeutic agent with the help of your gut bacteria.1 Hydroxocobalamin is red in color and plays an integral part in DNA replication and synthesis, proper
Methylcobalamin, also referred to as MeB12 and MeCbl, is a member of the cobalamin family and is one of the naturally occurring coenzyme forms of cobalamin found in the human body. Structurally, Methylcobalamin exists in octahedral form with Cobalt (III) at the center containing metal alkyl bonds[1]. It is considered an equivalent to cobalamin and
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