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Predicting High Homocysteine with MTHFR C677T

The authors Wang et al (2014) studied the ability of MTHFR C677T  to predict high homocysteine in Chinese patients with hypertension. Overall, the 677TT genotype was consistently associated with higher homocysteine across the group, with the increase averaging 51%. The authors conclude that the MTHFR C677T polymorphisms could be used screening marker for severely high homocysteine.

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