Lee & Song (2014) conducted a meta-analysis to explore whether plasminogen activator inhibitors-1 (PAI-1) 4G/5G and MTHFR C677T polymorphisms are associated with susceptibility to Polycystic Ovarian Syndrome (PCOS). 9 studies examining PAI-1 with 2384 total subject were employed for analysis, along with 8 studies with 1270 total subjects for MTHFR C677T. Meta-analysis of the results showed no correlation between PCOS and PAI-1 allele overall, with specific associations found between Turkish and Asian populations found. Overall, no study subjects showed an association between PCOS and the C677T allele.
MTHFR Support or MTHFR Support Australia is the world’s first dedicated MTHFR clinic. Pioneers in Health, we empower our patient’s lives through Science & Genetics.
CONTACT
Clinic Reception
+61 2 9908 1888
info@mthfrsupport.com.au
General Inquiry
enquiries@mthfrsupport.com.au
Suite 216, 40 Yeo Street, Neutral Bay NSW 2089
P.O. Box 1265Neutral Bay Junction NSW 2089
STAY CONNECTED
Sign up for our monthly newsletter with current MTHFR research, health tips, recipes, special offers and news about upcoming events including Carolyn’s live Q&A sessions.
Subscribe
Follow us on social media
