Association between a single nucleotide polymorphism in MTHFR gene and polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is the most common endocrine–metabolic disorder, affecting 5–10% of reproductive age women. According to the American Society for Reproductive Medicine/European Society for Human Reproduction and Embry- ology (ASRM/ESHRE) Rotterdam consensus in 2003, polycystic ovaries, oligo/anovulation or hyperandrogenism are often features of PCOS [1–4].

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