Schizophrenia

Schizophrenia

Share This Post

What is Schizophrenia?

Schizophrenia is a sever mental disorder (or group of disorders) characterised by a disintegration of the process of thinking, of contact with reality, and of emotional responsiveness.

Delusions and hallucinations (especially of voices) are usual features, and the individual usually feels that their thoughts are being controlled by, or shared with, others.

Individuals often become very socially withdrawn and they lose energy and motivation.

Research

1. High levels of homocysteine have found to be a risk factor for schizophrenia. Therefore, Kevere et al (2014) wished to further examine the link between the level of homocysteine, the MTHFR C677T mutation and patients with schizophrenia. Levels of homocysteine were found to be highest in the schizophrenic group in comparison to the control group, particularly in those with the CT genotype. Overall, this study found those with increased blood homocysteine levels and the C677T mutation were at an increased risk of developing schizophrenia, especially in those with paranoid or episodic schizophrenia.

Article Here 

2. Lochman et al (2014) state a possible link between MTHFR C677T mutations, high homocysteine and schizophrenia. Through examining a group of schizophrenic patients, an increased risk of schizophrenia presentation was associated with MTHFR 677 CT and TT mutations when compared to healthy people. The authors also studied the relationship between C677T mutations and other polymorphisms associated with schizophrenia, and found a link with the ADRA2A polymorphism which governs the release of neurotransmitters (brain chemicals) from nerves within the brain. This study shows there could be malfunctioning occurring a genetic level with both the nervous system and methylation cycle, which is increasing the risk of schizophrenic development.

Related Posts

Fertility

How the MTHFR gene mutation Affects fertility and pregnancy

One of the most common things I hear is the utter confusion many people find themselves in after they: Just discovered the MTHFR gene mutation ...
Read More →
Genetics
Conditions

The COMT-Dopamine Connection: Why Your Patient Isn’t Lazy—They’re Biochemically Flatlined

When a patient presents with low motivation, emotional flatness, addictive behaviours, or an inability to complete even simple tasks, it’s easy to mistake them as ...
Read More →
How to find out if you have the MTHFR gene mutation
Genes

How to find out if you have the MTHFR gene mutation

How to find out if you have the MTHFR gene mutation? MTHFR is an essential enzyme involved in the metabolism of dietary folate and links ...
Read More →
Chemical sensitivity
Conditions

Chemical sensitivity

Chemical sensitivity is a chronic medical condition characterised by symptoms that the affected person attributes to low-level chemical exposure. Commonly accused substances include smoke, pesticides, ...
Read More →
What Is Glyphosate And How Can It Affect Our Health?
MTHFR

What Is Glyphosate And How Can It Affect Our Health?

Roundup is a popular brand of herbicide by Monsanto and has been making rounds not because of how great a product it is but because ...
Read More →
How Camping Can Improve Your Sleep
Genes

How Camping Can Improve Your Sleep

Our Environments Are Artificial In today’s age our environments are almost completely artificial, we have artificial light, artificial environments, artificial food (think packaged and fast ...
Read More →
Scroll to Top
Carolyn Ledowsky

Stay Connected!

Sign up for our monthly newsletter with current MTHFR research, health tips, recipes, special offers and news about upcoming events including Carolyn’s live Q&A.

Subscribe