Cleft Palate

Cleft Palate

Share This Post

What is Cleft Lip or Palate?

A fissure in the midline  of the palate due to the failure of the two sides to fuse in embryonic development. Only part of the palate may be affected, or the cleft may be extend the full length with bilateral clefts at the front of the mouth. The cleft may be accompanied by a split lip and tooth formation disturbances.

Cleft palates can be corrected by surgery.

Research

Mothers of children born with Cleft Lip or Palate were examined for involvement of the MTHFR C677T & A1298C mutation, folic acid supplementation and environmental exposure. Ibarra-Lopez et al (2013) found there to be an increased risk of having a child with C L/P in mothers with C667T or 677TT mutation in comparison to those with the normal C677C genotype. A lack of folate supplementation in the first trimester also contributed to the development of C L/P, which was further compounded by the presence of T677T or C677T MTHFR polymorphism. No association with A1298C in mothers and children with C L/P was found.

Article Here

 

 

Related Posts

ADD/ADHD
Conditions

ADD/ADHD

What is ADD/ADHD? Attention deficit disorder/attention deficit hyperactivity disorder (ADD/ADHD) is characterised by short or poor attention span and impulsivity, with or without hyperactivity. ADD/ADHD ...
Read More →
Healthy Homemade Chocolate
MTHFR

Healthy Homemade Chocolate

Ingredients: 1 cup  cocoa butter 1 cup  cocoa powder ½ cup  honey or to taste (using half this amount or less will make a bittersweet ...
Read More →
Stir-Fried Asian Greens (with chicken or fish)
MTHFR

Stir-Fried Asian Greens (with chicken or fish)

Ingredients: 1 tsp sesame oil 1 tsp olive oil 2cm piece of ginger, grated 1 clove of garlic, crushed 1 birds eye chilli, finely chopped ...
Read More →
What Copper Does For Us
MTHFR

What Copper Does For Us

Have you ever seen copper-free multi-vitamins or read about the zinc to copper ratio and wondered if you need more or less copper to support ...
Read More →
How Prebiotics Can Support Gut Health, Metabolic Syndrome and Fertility
MTHFR

How Prebiotics Can Support Gut Health, Metabolic Syndrome and Fertility

In natural medicine, it’s a widely accepted notion that having a healthy gut leads to better health overall. There is growing evidence of the crucial ...
Read More →
Mediterranean Vegetable Soup
MTHFR

Mediterranean Vegetable Soup

Ingredients: 1 tbsp olive oil 1 onion, diced 1 carrot, halved lengthwise and sliced 2 stalks celery, sliced 3 cloves garlic, crushed 2 cups vegetable ...
Read More →
Scroll to Top
Carolyn Ledowsky

Stay Connected!

Sign up for our monthly newsletter with current MTHFR research, health tips, recipes, special offers and news about upcoming events including Carolyn’s live Q&A.

Subscribe