Articles

MTHFR

MTHFR and the Brain: Untangling the Genetic and Biochemical Links to Neurological and Psychiatric Disorders

When we talk about MTHFR polymorphisms, most practitioners think about methylation, cardiovascular risk, or pregnancy complications. But increasingly, the research is pointing to a different ...
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Conditions

Choline – The Unsung Hero of Methylation

Methylation is a fundamental biochemical process that underpins everything from gene regulation and detoxification to neurotransmitter production and liver health. Most health practitioners are familiar ...
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gut bug
Conditions

How Gut Bugs and Inflammation Steal Your Tryptophan (and Your Happiness)

You’ve heard the phrase “the gut-brain axis.” But in clinical practice, that connection runs deeper than many practitioners realise—especially when it comes to tryptophan metabolism ...
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Genetics
Conditions

The COMT-Dopamine Connection: Why Your Patient Isn’t Lazy—They’re Biochemically Flatlined

When a patient presents with low motivation, emotional flatness, addictive behaviours, or an inability to complete even simple tasks, it’s easy to mistake them as ...
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Carolyn Ledowsky

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