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Be a part of important research to help understand how Folate may stop recurrent miscarriage.

Ethics approval has now been granted and the trial is ready to proceed. 

Ethics Number: ETH22-7218 | ANZCTR: ACTRN12622001577707

Carolyn Ledowsky

Carolyn Ledowsky and the University of Technology Sydney are conducting a pilot clinical trial for couples with recurrent pregnancy loss.

Not all Folate is the same

Folic acid has traditionally been used in prenatal supplements, however research has identified that some people may require a more active form of folate to support fertility.

Who can this help?

This trial builds on previous research, which identifies that some people may require different forms of folate to support a successful pregnancy and prevent miscarriage. By better understanding the role of different Folates during pregnancy, we can better help those going through infertility and miscarriage.

What is the trial about?

We will invited 60 couples with recurrent miscarriage to join the pilot study. They will then randomly be assigned to one of two groups:
     a) Couples that will receive a folic acid based prenatal multivitamin
     b) Couples that will receive a methyl folate based prenatal

The couples will then take the prenatal product for a minimum of 9 months.

The objective is to see if we can take this procedure and protocol to a much larger audience and evaluate if miscarriages were reduced in one of the two groups.

We are talking about pregnancy, why do we need men as well?

Prenatal care for men has been shown to be just as important to the conception and fertility process as women.

What will the results tell us?

We will know if the way we have conducted this trial can be expanded to a lot more people later on. We will also have data on whether one group over the other had an improved pregnancy outcome.

What will the funding be used for?

Your donation will support this research by supplying;

  • Shipping and distribution of the multivitamins to the participants
    Blood collection funding – we need to raise over $13,000 to ensure we can test key blood markers like red cell folate, serum folate, unmetabolised folic acid and homocysteine.
  • This will help us understand what different forms of folate do to blood markers.
  • We need $50 vouchers as a thank you for participants. We will need 120 of these.

How can you help us?

Any donation no matter how small will help. If you are concerned about the increasing rate of miscarriage world wide then helping fund this research will help support key knowledge into the prevention of multiple miscarriage.

Would you like to join this research?

Would you like to participate in a clinical trial using different forms of folate to help prevent miscarriage?

If you would like to know more information about this trial please contact the lead researcher, Carolyn Ledowsky:
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Carolyn Ledowsky

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