Carolyn Ledowsky

AbstractFolate is required for metabolic processes and neural development. Insuring its adequate levels for pregnant women through supplementation of grain-based foods with synthetic folic acid (FA) in order to prevent neural tube defects has been an ongoing public health initiative. However, because women are advised to take multivitamins containing FA before and throughout pregnancy, the …

Is High Folic Acid Intake a Risk Factor for Autism?—A Review Read More »

AbstractBackground: Serum total folate consists mainly of 5-methyltetrahydrofolate (5-methylTHF). Unmetabolized folic acid (UMFA) may occur in persons consuming folic acid–fortified foods or supplements. Objectives: We describe serum 5-methylTHF and UMFA concentrations in the US population ≥1 y of age by demographic variables and fasting time, stratified by folic acid–containing dietary supplement use. We also evaluate factors associated with …

Unmetabolized Folic Acid Is Detected in Nearly All Serum Samples from US Children, Adolescents, and Adults Read More »

Abstract There are increasing concerns that exposure to unmetabolized folic acid, which results from folic acid intakes that overwhelm the liver’s metabolic capacity, may be associated with adverse effects. In this paper, we examined the folic acid status of women of reproductive age in relation to dietary intake and the effect of folic acid supplementation …

Circulating Unmetabolized Folic Acid: Relationship to Folate Status and Effect of Supplementation Read More »

Courtney Cox has done something every couple struggling to conceive dreams about… she found the answer to the question:”Why do I keep miscarrying?”In recent years, the FRIENDS actress has opened up about her battle with recurrent miscarriages when trying to conceive her daughter, Coco, now 16 years old.Couples all around the world have connected with …

Courtney Cox Finds the Answers to Her Fertility Problems Read More »

Our genes shape most of what we look like and how our bodies work – the very fabric of our being. Humanity’s understanding of genetics has come a long way since Gregor Mendel, the Father of Genetics, carried out his fateful experiment on peas in 1865. Genes have been found to be intricately linked to …

Do MTHFR polymorphisms make you more susceptible to COVID-19? Read More »

Why getting a health check up should be at the top of your list The beginning of a new year is prime time for many people to set their health related resolutions and goals for the year ahead. Common health goals include things like; losing weight, quitting smoking, introducing an exercise regime or just aiming …

Healthy New Year’s Resolutions Read More »