Folate and Brain
Folate and Brain Is 5-MTHF (methylfolate) better for the brain than folic acid? Methylenetetrahydrofolate reductase (MTHFR) is required for the formation of 5-MTHF in the body, and thus MTHFR deficiency reduces the distribution of folate and the balance between folate for nucleotide synthesis as well as methionine synthesis.[i] The consequences are an increase in homocysteine …